Intertek ASG Laboratory, Manchester, UK

Physical Property Measurement

Intertek ASG is able to provide a wide range of physical property measurements on aqueous solutions, fluids, liquids and solids. Applications include pharmaceutical R&D, registration of new chemicals (REACH, NONS legislation) and product development and technical support for many industry sectors. Experiments are carried out to the appropriate regulatory standards of GLP and GMP/cGMP.

Typical examples of physical property measurements available from Intertek ASG include:

asg.nwtc@intertek.com

+44 (0) 161 721 5247

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Measurements on aqueous solutions

Measurements on fluids and liquids

• pH, pKa and multiple pKa
• logP
• logD
• Aqueous solubility
• Conductivity
• Redox potential
• Corrosion studies
• Partition coefficient e.g. octanol:water by shake flask or HPLC

• Viscosity, inherent and intrinsic viscosity
• Freezing point and boiling point
• Vapour pressure
• Surface tension
• Density and specific gravity
• Refractive index and optical rotation

Measurements on crystalline and amorphous solids

• XRD, Determination of crystallinity
• Pharmaceutical thermal properties
• Differential Scanning Calorimetry - DSC and MDSC
• BET surface area measurement
• Melting point
• Density
• Electron microscopy
• Light microscopy and optical studies e.g. birefringence
• Light reflectivity and scattering measurements on solid surfaces (with integrating sphere)

For information of the prediction of physical properties see:

• Physical Property Prediction