Intertek ASG Laboratory, Manchester, UK > Advanced Morphology Services > Dynamic Light Scattering

Dynamic Light Scattering

Dynamic Light Scattering (DLS), also known as Photo Correlation Spectroscopy (PCS) or Quasi-Elastic Light Scattering (QLS, QELS), is a technique for measuring the size of particles typically in the sub micron region. Intertek ASG have invested in a new Malvern Zetasizer Nano ZS system that can perform a combination of the three most important parameters for the colloid and polymer chemist: particle size analysis, zeta potential measurement and molecular weight measurement. The new technology incorporated in these systems provides unequalled sensitivity and versatility. The patented NIBS optics incorporated into the Nano ZS also allows measurement of samples with little or no dilution.

All instrumentation is qualified to GLP and GMP standards allowing Intertek ASG data to be used in regulatory projects and pharmaceutical QC.

Measurements Available:

• Particle Size Analysis

NIBS technology enables measurements of particles and molecules from 0.6nm to 6 microns

  

• Zeta Potential

M3-PALS technology enables accurate measurements of zeta potential in aqueous and non-aqueous dispersions

  

• Molecular Weight

An avalanche-photodiode detector and fibre detection optics give the sensitivity and stability required for absolute molecular weight measurement

Applications:

• Protein characterization
• Monoclonal antibody characterization
• Electrostatic aggregation
• Static light scattering for absolute molecular weight determination
• Characterization of protein melting point
• Protein formulation stability

asg.nwtc@intertek.com

+44 (0) 161 721 5247

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